PSM Biological Research <p style="text-align: justify;">PSM Biological Research (ISSN; 2517-9586) is a peer-reviewed, open access, multidisciplinary,&nbsp; international journal that publishes research on all aspects of biology and allied sciences.</p> en-US (PSM Biological Research) (MANI MUGHAL) Sun, 24 Jun 2018 09:13:52 +0000 OJS 60 Hematological Profile in Schistosoma mansoni Infected Mice Treated with Commiphora molmol Extract Compared with Praziquantel <p style="text-align: justify;">As <em>Schistosoma mansoni</em> worms inhabit the portal triad of infected hosts, deleterious changes were encountered in the blood picture. The aim of the study is to explore the damaging hematological effects due to <em>S.mansoni</em> infection in albino mice before and after treatment with either <em>Commiphora molmol</em> extract or Praziquantel. Seventy two albino mice were recruited in this study and divided into 4 groups of 18 mice each, 54 of them were infected with <em>S.mansoni</em> cercariae.7 weeks post-infection, infected animals were treated with 500 mg/kg either as a single dose for 2 days in Praziquantel or for 5 consecutive days in <em>Commiphora molmol</em> extract. Blood samples were collected at 1, 2 and 4 weeks after treatment for assessment of complete blood counts (Hb, erythrocytes count, haematocrite value, MCV, MCH, MCHC, Platelet count, leucocytic count and differential leucocytic counts).<em>S.mansoni</em> infection resulted in multiple damaging effects of the blood profile on infected non-treated hosts as evidenced by decrease in red blood cells and platelets and rise in white cells with the advance of infection. Treatment with Praziquantel corrected the blood profile of erythrogram and the platelet count in progressive manner with advance of time after treatment more than <em>Commiphora molmol</em> Extract. This study declared that Praziquantel and <em>Commiphora molmol</em> extract were safe drugs without dverse hematological effects on infected treated mice with more ameliorative action achieved by Praziquantel than <em>Commiphora molmol</em> extract.</p> Mohammad Aziz Alkazzaz, Amer Ragheb Adel Aziz, Ehab K Elmahalawy, Amal A Hassan ##submission.copyrightStatement## Sun, 24 Jun 2018 09:13:25 +0000 Effect of Drought Stress on the Growth and Morphological Traits of Eucalyptus camaldulensis and Eucalyptus citriodora <p>Drought stress is the basic ecological stress in growth and development of the trees. A pot experiment was designed to analyze the growth and germination potential of<em> Eucalyptus camaldulensis </em>and <em>Eucalyptus citriodora</em> against the drought stress via completely randomized designed experiment with four replications along with four stress intervals. Seedlings were raised in pots by irrigating at four different levels i.e. 1 day (Wo), 5 day's (W1), 10 day's (W2) and 15 day's (W3). Several morphological parameters were studied. The plant height of both the species was maximum when the plants were irrigated after 1 day time interval and it gradually decreased as the irrigation interval increased. Root length varied drastically against the influence of the drought. Maximum root length 6.5 cm was observed in <em>E. camaldulensis</em> when the water was applied after 1 day interval followed by the <em>E. citriodora</em> yielding 6.1 cm of the root length against the same treatment. As the irrigation interval increased, the shoot fresh weight decreased leading to the minimum value for the shoot fresh weight at the treatment W3. Root dry weight was more as compared to <em>E. citriodora</em> for all treatments. Maximum root-shoot ratio (5.2) was observed in <em>E. camaldulensis</em> when the water was applied after 5 day interval (W1). Hence, we suggest that <em>Eucalyptus</em> plantation should not be done at fertile agricultural lands as its plantation can be very favorable in waterlogged and saline conditions.</p> Muhammad Sohail Yousaf, Taimoor Hassan Farooq, Irfan Ahmad, Matoor Mohsin Gilani, Muhammad Haroon U Rashid, Narayn Prasad Gautam, Waqar Islam; Muhammad Asif; Pengfei Wu ##submission.copyrightStatement## Sun, 24 Jun 2018 10:58:19 +0000 Native Yemeni Plumbago auriculata as a Promising Antioxidant and Antifungal Plant against Different Fusarium species <p style="text-align: justify;">Plants and plant derived metabolites are believed as rich source of antifungal and antioxidant agents, with their fewer side effects, they are finding their way into pharmaceutical derivatives. The present study was undertaken to investigate the methanolic leaves and flowers extracts of <em>Plumbago auriculata </em>for their potential activity against phytopathogens and antioxidant efficiency. The extracts were evaluated against different pathogenic <em>Fusarium</em> species; <em>F. verticilloides, F. oxysporum </em>and <em>F. solani</em> using agar well diffusion method. <em>F. oxysporum</em> showed the higher susceptibility of inhibition with all extracts, followed by <em>F. solani </em>and <em>F. verticilloides </em>in case of leaves extracts, while <em>F. verticilloides </em>was the most sensitive after <em>F. oxysporum </em>in case of flowers extracts. It was clear that 75% concentration was the most effective among all concentrations tested. In DPPH (free radical scavenging assay) for antioxidant evaluation for the plant extract. The flowers extracts showed higher antioxidant activity than those of leaves with a dose-dependent manner. This study support the use of this herbal plant as antioxidant and antifungal agent to control <em>Fusarium </em>species especially <em>F. oxysporum </em>the causative agent of <em>Fusarium </em>wilt of tomato.</p> Aziza Taj Al-Deen, Hala J Al-Jobory ##submission.copyrightStatement## Mon, 25 Jun 2018 00:00:00 +0000 Соmрutаtiоn оf Sеераgе аnd Еxit Grаdiеnt thrоugh а Hоmоgеnеоus Еаrth Dаm withоut Filtеr Drаin by using Gео-Slоре (SЕЕР/W) Sоftwаrе <p style="text-align: justify;">In this study, SЕЕР/W wаs usеd tо dеvеlор а finitе еlеmеnt mоdеl оf а hоmоgеnоus еаrth dаm аnd fоr this рurроsе Hub dаm wаs sеlесtеd. Twо diffеrеnt саsеs i.е. (i) with filtеr drаin аnd (ii) withоut filtеr drаin wаs studiеd tо сhесk thе bеhаviоr оf thе dаm in tеrms оf sеераgе flux аnd еxit grаdiеnt rеsресtivеly. Thе sоftwаrе wаs аlsо usеd tо simulаtе thе рhrеаtiс linе bеhаviоr fоr bоth саsеs. Thе FЕ mоdеl wаs соmрrisеd оf fоur diffеrеnt tyреs оf еlеmеnts i.е. triаngulаr, squаrе, rесtаngulаr аnd trареzоidаl. Fоr саsе (i) thе dоmаin is disсrеtizеd intо а mеsh by 12,346 еlеmеnts thrоugh рlасеmеnt оf nоdаl роints 12,495 аnd fоr саsе (ii) 12,305 еlеmеnts аnd 12,399 nоdаl роints wаs usеd. Thе оutсоmе оf thе simulаtеd rеsults shоwеd thаt thе dаm is sаfе аgаinst рiрing, аt its оriginаl dеsign аs thе instаllаtiоn оf а filtеr drаin fоund wоrking еffесtivеly in rеduсing intеrnаl wаtеr рrеssurе within thе dаm аnd its fоundаtiоn. Fоr саsе (i), thе рhrеаtiс linе shоwеd а nоrmаl trеnd аs it is fаlling intо thе filtеr drаin with оvеrаll minimum sеераgе flux оf 2.513 x 10<sup>-4</sup> ft<sup>3</sup>/sес/ft аnd еxit grаdiеnt аt dоwnstrеаm tое 0.351 rеsресtivеly. Hоwеvеr, fоr саsе (ii) thе dаm shоwеd аn irrеgulаr bеhаviоr аs thе рhrеаtiс linе trеnd wаs fоund аbnоrmаl аs it сuts thе dоwnstrеаm slоре оf thе dаm аnd аbоut (65.419% – 71.085%) mоrе еxit grаdiеnt wаs rесоrdеd fоr еасh sсеnаriо.</p> Imrаn Аrshаd, Muhаmmеd Munееr Bаbаr ##submission.copyrightStatement## Thu, 19 Jul 2018 00:00:00 +0000